Caffeine Nicotine Strychnine Americas 07-25-2021-23:27 draft

 https://emergency.cdc.gov/agent/strychnine/basics/facts.asp

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https://www.britannica.com/science/curare

https://www.sciencedirect.com/topics/medicine-and-dentistry/curare

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234642/

https://en.wikipedia.org/wiki/Strychnine

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https://biocyclopedia.com/index/biotechnology/microbial_biotechnology/secondary_metabolites/biotech_antibiotics.php

Step Down Decontaminations; Antibiotics by Nicotine/caffeine/plant/etc., etc.

Table 16.2. Antibiotics produced by microorganisms.

Microorganism	Antibiotics*	Applications
Bacteria :
Bacillus brevis	Tyrothricin (G+, G-)	Mouth and throat infection
B. polymyxa	Polymyxin B (AT)	UTI, gastroenteritis
B. subtilis	Bacitracin (G+)	Dermatitis, superficial pyogenic infection, dysentery
Streptococcus cremoris	Nisin (G+)	In cheese, food preservation (non-medical use)
Actinomycetes:
Micromonospora purpurea	Gentamicin (G+, G-)	UTI, abscess
Nocardia, mediterranei	Rifamycin (My)	Meningitis
Streptomyces griseus	Streptomycin (G+, G-, My)	Tuberculosis
S. aureofaciens	Tetracyclines *(G+, G-)	Cholera, tetanus, UTI
S. erythreus	Erythromycin (G+)	Cholera, tetanus, arthritis
S. noursei	Nystatin (AF)	Skin lesions
S. spheroides	Novobiocin (G+)	Abscess
Fungi:
Cephalosporium acremonium	Cephalosporins (G+, G-)	UTI, pneumonia, meningitis
Penicillium chrysogenum	Penicillin (G+)	Pneumonia, pharyngitis
P. griseofulvum	Griseoftilvin (AF)	Skin and hair lesions
P. notatum	Penicillin (G+)	Fever, pneumonia, genital infection

UTI, Urinary tract infection; *Antibiotic spectrum; G+, Gram positive bacteria; G-, Gram negative bacteria; My, Mycobacteria, AF, Antifungal; AT, antitumour.

Among the antibiotics discovered so far, there are 4 major groups which are most extensively used throughout the world : the penicillins (Fig. 16.2), cephalosporins, tetracyclines and erythromycins (Fig. 16.3).

https://biocyclopedia.com/index/biotechnology/microbial_biotechnology/secondary_metabolites/biotech_antibiotics.php