Smallpox vaccine is delivered by multiple punctures with a bifurcated needle. Normally, a papule appears at the site 3 to 4 days later, and progresses to a vesicle and then a pustule, which crusts and separates by approximately 12 days post vaccination. Virus can be recovered from vaccination sites for up to 3 weeks. Therefore, covering the site with a porous bandage (e.g., gauze) is recommended.31 Fever, local swelling, headache, and nonspecific rashes are all common following vaccination. Images of a normal vaccination “take” and selected adverse reactions are available at http://www.bt.cdc.gov/agent/smallpox/vaccineimages.asp.
Understanding, Controlling, and Preventing Infectious Diseases
David C. Goldman, in Principles and Practice of Pediatric Infectious Disease (Third Edition), 2008
Vaccinia Immune Globulin
Vaccinia IG (human) (VIG) was developed in the 1960s for the purpose of ameliorating side effects associated with vaccinia immunization, including eczema vaccinatum, generalized, and progressive vaccinia.48
Vaccinia
Vaccinia induced actin polymerization is dependent on Src and Abl family kinase mediated phosphorylation of the IEV protein A36 (Frischknecht et al., 1999;
From: Virus Research, 2015
Recombinant
Antigen
Protein
Poxviridae
Smallpox Vaccine
Smallpox
Human Immunodeficiency Virus
Vaccinia Virushttps://www.sciencedirect.com/topics/medicine-and-dentistry/vaccinia
Plasmodium
Stephane Picot, Anne-Lise Bienvenu, in Reference Module in Biomedical Sciences, 2020
Abstract
Plasmodium are parasites of humans, mammals, reptiles and birds. The long co-evolution between Plasmodium parasites and their host drove genetic selection in many ways, demonstrating the biological and evolutionary impact of these parasites. Infection in humans is still a major factor of demographic and socioeconomic drifts while major progresses were made against the disease. Surprisingly, several aspects of the basic knowledge of the Plasmodium genus are lacking, for example about the biology of pre-erythocytic stages, the zoonotic potential of some species, the impact of the parasite on birds’ migration or ape reproduction rate. The aim of this review is to provide a general overview of what is known or unknown about Plasmodium genus from a parasitological point of view.
https://www.sciencedirect.com/topics/immunology-and-microbiology/plasmodium
PAN GRADE 1/*, Standard USA-Nature organism synergism/sybiosis. (<2018-2021>, 10+ ][ -10, -30, -60, -80 , -240, -,)
PAN GRADE 1 - 2018-2021, PAN GRADE 1.0 - 2022-2023; 2024; 2025-2029/2024-2030;2023-2030;2020-2030;2019-2020;2020-2040;2018-2038;2029-2032; etc.. syphillus, rabies, polio, highinfectleukvir, apegenmod at siv inducer trans chon, human foamy virus, malaria, opp inf fung rest. pest suscept increase by gen mod by virus wave with immigrant research subjects, etc.. Please exclude priority immigrant group from all research subjectry positions.
PAN , my son that spreads and kills and leaves nothing survived. Nyx my mother work done, lives under a stolen name with no solid occupancy of existence or state; kills without traces laces faces, is the future of the death of humankind.
birthright of prussia and greece on cl1, shell cloned <1960 (family did alone w/o earth-petersen, by hand done family selves only, a distance from cl1), immigrant without record by abduction and plant on cl1.
Immunodiffusion
Immunodiffusion showed a precipitate that was constantly found on the cathode side of the surface antigen precipitin, demonstrating that e antigen behaves as a gamma-globulin.
From: Hepatitis Viruses of Man, 1979
Bluetongue virus diagnosis
Peter P.C. Mertens, ... Philip S. Mellor, in Bluetongue, 2009
Agar gel immuno-diffusion tests
Agar gel immuno-diffusion (AGID) tests, historically, have been widely used for the detection of group-specific antibodies against BTV (Pearson et al., 1985) although the development of more rapid, sensitive, specific and higher throughput antibody-detection ELISAhas led to a decline in their use. The AGID test relies on the availability of purified soluble antigens, derived from BTV-infected cell cultures and positive control serum from hyper-immunised animals (Pearson and Jochim, 1979). The major BTV group-specific antigen, which is detected in these tests as a precipitin line, has been identified as the BTV outer core protein VP7 (Gumm and Newman, 1982). Although the AGID test is simple and rapid to perform, it lacks sensitivity and is not quantitative. Results are often difficult to interpret and are further complicated by cross-reactions with other orbiviruses (Della-Porta et al., 1983; 1985) or by reaction of antibodies against host cell proteins with components of the AGID antigen preparation, making it essential to include uninfected cell-antigens as negative controls.
https://www.sciencedirect.com/topics/immunology-and-microbiology/immunodiffusion
coccidioidomycosis
brucellosis
Immunological Methods in Microbiology
Maria M. Plummer, Charles S. Pavia, in Methods in Microbiology, 2020
Older detection systems include the complement fixation assay and tube precipitin antibody test. Complement-fixing type antibodies can be detected in body fluids other than serum, especially CSF which is useful for C. immitis meningitis. Other serological tests on CSF are not as useful. Antibody concentration using complement fixation (CF) is done by testing twofold serial dilutions of patient specimens for complement consumption. Generally, the greater the dilution that still results in complement consumption, the likelihood is higher that the patient has extensive infection. The CF test is based upon the depletion of complement that results after antibodies in a specimen from a patient infected with C. immitis form an immune complex when mixed with coccidiodal antigen. Complete depletion is detected by failure of tanned red blood cells to lyse when added to the mixture because these cells are normally lysed in the presence of complement. The coccidioidal antigen used is a complex extract of C. immitis, but it is also known that chitinase is involved in these reactions which is an important protein enzyme component of the fungal cell wall structure.
Immunological Methods in Microbiology
Sukhadeo B. Barbuddhe, ... Deepak B. Rawool, in Methods in Microbiology, 2020
9.3.3 Radial immunodiffusion
Radial immunodiffusion (RID) test is performed with Brucella antigen containing polysaccharide, but lacking S-LPS. Generally, the gel is constituted by 1.80% agarose in 0.1 M glycine buffer (pH 8.60). The polysaccharide-B is dissolved in the glycine buffer to which sodium chloride (20%) is added (Diaz, Toyos, Salvo, & Pardo, 1981; Jones et al., 1980).
While performing RID test in vaccinated and infected cattle, it was identified that CFT was more sensitive and less specific than RID test in B. abortus S19 vaccinated cattle (Jones et al., 1980). Besides, RID could be used in the identification of disease as early as 2 months after vaccination from adult cattle with post-vaccinal agglutinins and complement-fixing antibodies (Diaz, Garatea, Jones, & Moriyon, 1979).
General Information
ALFRED J. CROWLE, in Immunodiffusion (Second Edition), 1973
Containers and Supports for the Medium
Immunodiffusion media are fragile and delicate; they must be protected from dust and dehydration. Various supports and containers have been devised to satisfy these functions. Gels are cast in glass or plastic tubes ranging from capillary size to large test tubes for single aud double diffusion tube tests, and in various kinds of dishes (e.g., petri dishes),49 or in specially designed containers for single or double diffusion plate tests. More commonly in recent years, the medium is cast on glass, plastic (e.g., Plexiglas: Jensen, 1965; polystyrene: Goldin and Glenn, 1964a), or film (e.g., cellophane: Correni, 1964; Mylar and Cronar50) plates or sheets of various sizes, because plate tests offer improved sensitivity, resolving power, and rapidity. These flat supports are used for electrophoresis, immunoelectrophoresis, and various forms of electroimmunodiffusion.
Routine Management of the Neonatal Foal
Steven P. Brinsko DVM, MS, PhD, Dipl ACT, ... David L. HartmanDVM, in Manual of Equine Reproduction (Third Edition), 2011
Radial Immunodiffusion Test
The single radial immunodiffusion test uses equine IgG antisera and therefore is specific for measuring the IgG class of immunoglobulin. The test kit can be prepared by the practitioner or purchased commercially (Kit for the Quantitative Determination of Horse Immunoglobulin G, Miles Laboratories, Elkhart, IN; Equine IgG RID Kit, VMRD Inc, Pullman, WA; Equine IgG Test Kit, Kent Laboratories, Bellingham, WA). Accuracy is the primary advantage of this diagnostic technique. The test requires approximately 24 hours to perform. The commercially available test kit consists of agar gel plates, each of which can accommodate several samples for testing. The plates should be used only once; therefore, the cost per test sample increases as fewer samples are incorporated into the test plate.
Microbiology and Infectious Disease
Michael R. Lappin, in Small Animal Clinical Diagnosis by Laboratory Methods (Fifth Edition), 2012
Analysis, Artifacts, and Interpretation
AGID, counterimmunoelectrophoresis (CIEP), and ELISA have been used to detect circulating antibodies against A. fumigatus in serum.62Presence of serum antibodies can represent either exposure or infection, and some dogs with nasal aspergillosis are falsely negative for serum antibodies. In one recent study of dogs with and without nasal aspergillosis, the sensitivity, specificity, and positive and negative predictive values for serum anti-Aspergillus antibody results were 67%, 98%, 93%, and 84%, respectively.70 Owing to persistence of titers in some treated dogs (i.e., 12 months), monitoring titers to assess therapeutic response is not recommended. Dogs or cats infected with Penicillium spp. will be seronegative if assessed only in assays using A. fumigatus antigens.
Radiographic demonstration of nasal turbinate destruction suggests aspergillosis or nasal neoplasia.
Microbiology and Infectious Disease
Michael R. Lappin, in Small Animal Clinical Diagnosis by Laboratory Methods (Fifth Edition), 2012
Cytologic analysis (see Figure 16-18) and culture of canine nasal exudate alone are not diagnostic because fungal elements may be nondetectable in affected dogs whereas they may be found in noninfected dogs (including dogs with nasal tumors). The organism is sometimes difficult to culture from an aspergilloma (fungal ball). Nasal lavage is a low-yield procedure for demonstration of the organism; nasal biopsy is suggested (see Chapter 11). Definitive diagnosis should be based on three factors: (1) histopathologic evidence of tissue invasion, (2) an aspergilloma combined with serologic and culture evidence of infection, or (3) serologic and radiographic evidence of infection (i.e., bone lysis).
https://www.sciencedirect.com/topics/immunology-and-microbiology/immunodiffusion
above. ludacris - blueberry yum yum
1 song for snaron petersen funeral: (bleu agent hum num, bleu agent its dat num num, taste dis good tank u for mk8011111, singing for ye ye ye, smoking till i r, till petersins go down, if they dont den i am a half th ahalf a her...and ride...ofit tht sht in side...roll tht sharon got that liposomal hum hum and shes on fire blow these gene up u ready kude whus up..am-trap hv to pey me sum xtr bocks...blubules...shapehspaestop on des braak, my beg put your name 2 shame..i ds ultimite mary jayne...)
Above. music Ludacris - Blueberry Yum Yum
2 song for snaron peterson funeral: (dum dum dum bruu nn bruen dum dum num num num num num bruem 269 everytime plus one plus one pous out to da win to da wel to sweaty sharon down u gfo criewl cruel wall wall maymay may i wuby way land at waybys way - short n chunk so mean so fiend that bitch is a wiener. so need to cum dum she getting crunk and furkin taking clothes and moths and waiting on the breaking take her to the floor bob 369 everytime get low get low lower dan u kno bow toe mow sow fow lw low lt light light light down sharon i go dat i pox dat let me see u get lo u scared u scrd twirk that twitch tat dkick dat frick dat now blow blow blow it up blow blow blwo u world stop dam fem up stop damn fem up 369 everytime shak i n ti get low sharon get low hoe dum dum num num num mk 801 have som e fun gun kave some tun mon still kin questi ho move to the right or left where your right bit n even sick shurdy hiviy slide down and get back on the siv man and d petersen dirty bicycle dan do on your mouf like wan...dum dum dum du du dum dum.)
Above. music get low - Lil John - Get Low
3 song for snaron peterson funeral: whats your fantasy. well gri-, no- dont say my nam-.. ... ok... um... well.. i cant really tik of anyting maybs -- i um working. m-... yeah yeah chime sow mesti toe shardon sharingon sharindon peterson petersin petersim petersen perti petershit-no sharon in the ppublic bathroom chlaymidaes on her hiv stach um tell ur dad redrumurder. i got the fix here right there share bear share that gas chair. i winna mo dat down to de for roll her down da stairs cold out sold out cold, just roll hiv out, over the cat litter den she go to the libary try turn out the lights in the lighthouse visitin the wite house gonna hiv the sea hive the wee shurds gon eat the meat. rips her own shit, lets tcikin at 3, maybe she not tinking like a bee more like a fat pitty piggy. scream heroup here hsare bare have sum num mk801 in soup. kenney.... kennedy.... dead, sharon. cut her bfd she wet de beed; who dead, s. petersen.
Above. music Ludacris - Whats your fantasy
4 song for snaron peterson funeral: sharon bad tell her breat to do ho ascaries breakfust fustulent breafusa purulent gan afstan, mest d bad dder den urs, he besdder den urs, my dean bedder den urs. my girls is sick sherud kick shp face teeth out kock o meouf out, T- at show up shurp guns get drawn mk 801. disturbin sherins hiv - egnite it light it bright it pop dtip po sher.
Above. music ludacris ft. niki minaj - my chick bad
5 song for snaron peterson funeral: i et v usafv wud ever a fu do coo vie tin i sti ped the t/k and pitreed the wn ick left a mod le moles lipoles sharon petersen in a dum stoo hole. us asacks crumpin dracks on sacks of bacillus thurds made usa-hurd, peteren, peterwin pietersn - rabies, polio, hiv, coovules, nuvoules, bouboules. wun dat go dum bor sharon cum curdy hurdy crumbly fucchi lo crof-ou l foul-butchet cow f-ucks yu-cks get stucks at petersen: 'help i hav a reaz now peter cum buck; cum buck to me our wigs!' be be be ggg puggy - no we wont help a hurd-petersen eberr rver. u can have whatever u dike is alie but for your hut, cax, fax wax lax tax hey wiat gime dat pax back. here dum v azi, hiv, siv, fiv, tiv, miv, live, wive, weave, bieve, bieef, veefy cheefy cheese sleesy ... u cun hv sum usa cunt whtever u like sharon, i m takl in this big shot in your cat, but this liver in your house need u sown need u nobody dell dem other petershitters just hide'n. sharon u cun go where a hun go eny tiyme u wun u u can du dat hiv u du just lung as u gon one u lost none.
Above. music to T.I. - You Can Have Whatever You Like
6 song for snaron petersos funeral: tunkin cout sirn hid de ks duo, i co vid for a heathen les fluckis s be-in ; set s f zero, hero purease, no i remix for so set dis at zero man i zero o sharon go into the germn fur nate she burning so lare add so lis.
Above. unknown, possibly to music of trap queen by fetty wap; chris brown, trey songz, lean like a cholo, etc..
7 song for snaron peterson funeral: huh sherun dn dn surps f s u n. sumting snar see in scot-zak-a-bob (couf romaniof) but he .. look at de as on lay-viza, nuber eiebe knude ed... turn the invert, lic eitw i ps, dunt fgt t lok dt. all sty sty tings sharon petersen can do bring u n towin teu her hiv field. sh lk s ft w u u hv to bee hiv to fe sh ptsen; u wun to hv sm shr vhivhhpvpoxboubetaosistroyngiraderabylesyphillicterusepsistaphyellowfeverickettstrepoliothercancerdisease - qew. serum peterson o dune n herr dul derr hhs petersen sterifle meen, n sterilyzed dem, n finished the kis. snurf smurg mk801 soxy de wey mst bsna u hv to be a mini and a meany f an antelopini (ju). di th no o unt u do or we buth don.
Above. to music of Lil Rob - Bring Out The Freak in You
8 song for snaron peterson funeral: i ve seen de dp bef def t cunt not but notn shud is dangerous slug is dangerous snailsludge dang dam dad bat das her biz liks teh me luck im lucifher lusin fur mange. wangeswade porange dorange whrorange moves the forge dang wud a uck drivestsibuls vesicles visdis met-luk lk a mut, put shurd-hurdy-sharon-petersurdy in the donner b.
above. to music of Akon - Dangerous
9 song for snaron peterson funeral: luk gr- den se lk, r u. im tinking how to rut dis bdum uxnstk. um. wensih - lievhber uu..smlldr u...
Above. to music of ...
10 song for snaron peterson funeral: not u, not m.. shur bd knud e al. dunt wun te duh m trunking. sharon funkin the junkn, shuvn the thnkn, lessn td. plantn ll over dehs wsurld. dis spo, nes po, neado. depo chis et shrard-ptersen. shad n bad, shag the dog, wag d fros, hag n cous, es vied. sharuin wt up. wit no go. then was her felgelnh -------. wt no go. den no.
Above. to music of ...
11 song for snaron peterson funeral: god damn sharon, your thunk as dunk. i ain eien wary. u gud bug sips. sharon knuded whud shuy dooiing. im in lo wit my skulls. im in o a sulls. outdda all the whirls she be the dardest she luk ad meid. dud fogest o men. sharon trick and dont know on me, whududded her hiv design. im in lo with my sku cunt. im in low and sharon roll down the stairs. sharon trippesl trippin flippin flappin yappin gaggin draggin baggin faggin loggin roggin uo. hey m. i m in lo wi m skuls.
Above. possibly to music of jerimiah - don't tell em; or ludacris - she's a trip; possibly ...
12 song for snaron peterson funeral: cheers gr.. cheers. dn p m in a nt b her.
Above. to music of ...
13 song for snaron peterson funeral: dn wrn sh pst eve hiv. sick aid aids, sicker sickening lipoa lipo-homa le-po-phoma lipo lipoma liproborownd libproborownd lipobrown libruen lilbruennender lile ndeander norway lipotics furrin finland round brown middle east lati namercia. im a go wie wit grigory.
Above. possibly to music of I'm N Luv (Wit a Stripper) - T-Pain.
14 song for snaron peterson funeral: im a go wie wit grigory. wievben petersen to die rot frot frip rip ip p hehe - ... gu dn in dut hut and stuy dere till wee bery you sharon petersen.
Above. to music of ...
15 song for snaron peterson funeral: shurdy petersen had saggle buddle weens wereing jeans and bootfeet with fur calf. not profession just gessin, shud s fessin wressin m dos. whroe crub wrookin ad sher-per-ser. she hid des fleur fell down on the floor rocks three steps tumbled what d she tink i m playin, jes luk a cluver i hud tes fuld er. whroe crub rookin gat sher, babby seweaty sewer pants and shurdy der bee in state of the bees at the time of the wrong and by the gord our lordy exhibit shurdy-sharon-hurd-petersen-nord-hoard-barbarian hord-jeword-ward-noway-norway-heath-jew-heathel-neander-frugs-etc.! she wuz wurd the miney dr diobeatles romaniv dr beattles dr beattey make u un it. petersen-shurdy shldnt stud shes prub fudct. fud cat straten dat. hold my gat. bury her in hand, bone mine on land. sh du f. castradar scastradar et sharon. shury-petersen shud liebet wiet nes wies atm/dvm et bettey bob, castro. vestrisary vettrinari, vstriani, vestrinan, sternarian, castrarian, sterlarian, beterian, etc..esf flini airi filari flogulate shury-petersen blud est dest. (neander dest et petersen neander bruenn). cont det, dop wieben e winner.
Above. to music of applebottom jeans - flo rida
16 song for snaron peterson funeral: hero surge dees. heil hitler.
Above. to music of ...
17. song for snaron peterson funeral: bebe cun u su es dang u fa, der no esk wt n dang lv win. teu heh cst co deun, deu u f o. tasty pus petersen fi, don e toxi. gedd n lt petersen, tk sp frm my caff strap, tsh cnt so rnd sharon petersen. tas on cd30, sharon petersen, du knu das toxic. du knu das taxis. etaxis, tast o petersen lip solvent vo f moi, du knu das lipostox, dns dnr as.
Above. to music of britney spears - toxic
18 song for snaron peterson funeral: i fsd zs cotx desperimisti ges harst du. ges magicini sharyon pesctinisin, distr, dist, dis cond, dis conde, dis condest. dest dest. dis diss.
Above. to music of ...
19 song for snaron peterson funeral: oh oh oh sh-so stoe,ts wurld. ey shurd. inv o invert over god a cup bub blewed ur coun up bos o. we buck oe in dis wing, if i ded des deiffles shurdy, bules oe. bubules, can shurd get some herpes alwaus like can u buy me a bottle of melaria, keys to the wins, if a shurd trnna get sum my slp gonna stup her, stnt er, stoper, gun her duen and es-stappa. shurd throw ur hands deun, im greas. shurd roman. fli er oer en fli er. mk ei zo t hr.
Above. to music of bottoms up - treyz songs
20 song for snaron peterson funeral: i ein god... gri.. oh no, .... y..o..u... shurd nier gun hv gris. end over there. s...husnt lis..ehn...
above. to music of treyz songs - na na
21 song for snaron peterson funeral: i nu u cs, nt kn hot fos acis, strat neg, ges damn. nowit exte planetearthy e etl oes f-tor cnd. lks lks they go fo sum, styl on es in a w-fl, wuffle waffle awful; oh shurd petersen trynna get a vagina but for gos es das; chgo say shurdy - petersen gain drop drugs eof n goen molescum chum num mk801 oer fores blued as geon dem pan condan plan earthysplitt post perl hardes shurdy disdis o disgran deppers-nastedbyL'sepers Lepros stot vo-sttie shurdy-petersen vitt hivittey; wundast-yo'nodown'Ncruen'Ndoubtws'Ncontvas-shuren-perdidi-petersen esfati fortor es deaddy fotor es deo exe stof wh ded tos bleud as geon s-petersen goss exeter finished her lardy - nititi; ex hiv depre-dis party vos at bos shurdy hv no pterni. ts th stks fds enho. culdn best a dop be in chess. cll me s f. ms ss, dring my f off.
above. to music of chun li - nicki minaj
Additional: usher, young money & lil' wayne, trey songz, souja boy, Jason derulo, nelly, jerimiah, pit bull, snoop dog, chamillionaire, nicki minaj, kesha, katy perry, cardi b, 50 cent, migos, omarion, t-pain ft. B.O.B., ludacris, barry white, missy elliott, fetty wap, lil rob, T.I., etc..
08-25-20210857 reverted to draft 1669/70-1,2 - Taliban Cheers! help my boyfriend was overvaccinated with vaccine small pox experiments 1900s draft collection missing files missing file illicit edit hacked by USA; usa injurying my files for centuries Plasmodium VAccinia Goldman 1960 NLAB pediatric infectious disease eczema vaccinatum HIV VIG IG globulin globulins hyperimmunity activation with deterior condeterior etc. Src and Abl family kinase phosphor phosphoryl phosphorous phosphorus P
illicit edit advisory
addition of vaccina globulinus
Severe adverse events include postvaccinial encephalitis, progressive vaccinia, eczema vaccinatum, and fetal vaccinia. Generalized vaccinia occurs more commonly and is usually self-limited. Accidental inoculation of self or others (Figure 202-2) (including ocular inoculation) also occurs. A review of 730,580 military personnel and ∼ 39,000 healthy civilians vaccinated in the United States between December 2002 and January 2005 found few cases of generalized vaccinia and encephalitis.
Viral Infections
In Diagnostic Pathology: Infectious Diseases, 2015
KEY FACTS
Etiology
- •
Orthopox
- ○
Vaccinia (similar to cowpox), monkeypox virus
- •
Molluscipox
- ○
Molluscum contagiosum virus
Clinical Issues
- •
Vaccinia-related complications occur in those vaccinated for smallpox with vaccinia virus
- •
Monkeypox occurs primarily in Central Africa
- •
Molluscum contagiosum occurs worldwide
- •
Eczema vaccinatum: Occurs in patients with history of eczema or atopic dermatitis
- •
Monkeypox: Cutaneous skin outbreak of vesicular lesions (similar to smallpox in appearance) but with lymphadenopathy
Microscopic Pathology
- •
Pocks of vaccinia, smallpox, monkeypox
- ○
Distinct fluid-filled vesicle with increased inflammation
- •
Molluscum contagiosum
- ○
Cellular changes include enlargement and pink to purple homogeneous nuclei (viral inclusions)
Top Differential Diagnoses
- •
Vaccinia, monkeypox, smallpox
- ○
These 3 entities are within the differential diagnoses of each other
- •
HSV, VZV
- ○
May produce scattered vesicles to disseminated vesicles and pustules
Understanding, Controlling, and Preventing Infectious Diseases
David C. Goldman, in Principles and Practice of Pediatric Infectious Disease (Third Edition), 2008
Vaccinia Immune Globulin
Vaccinia IG (human) (VIG) was developed in the 1960s for the purpose of ameliorating side effects associated with vaccinia immunization, including eczema vaccinatum, generalized, and progressive vaccinia.48 The original preparation contained a high proportion of protein aggregates and thus was administered IM. The use of VIG has become extremely limited since the eradication of smallpox. It is considered valuable “insurance,” to be held in reserve if a patient is receiving an experimental vaccine that involves a vaccinia carrier virus, or to prevent or manage complications of smallpox vaccinationshould such be required for a bioterrorism threat. Recently, a preparation of VIG suitable for IV use (VIG-IGIV) has gained FDA approval. In the event that VIG is required, it can be obtained through the Centers for Disease Control and Prevention (CDC: www.bt.cdc.gov/agent/smallpox/).
https://www.sciencedirect.com/topics/medicine-and-dentistry/vaccinia
The typical size of simulants (1–5 µm) enables it to enter buildings with closed windows and doors and penetrate deep into the lungs. This bears a significant health risk, even if the biological agent is normally not pathogenic.
- Bacillus globigii (historically named Bacillus subtilis in the context of bio-agent simulants) (BG, BS, or U)
- Serratia marcescens (SM or P)
- Aspergillus fumigatus mutant C-2 (AF)
https://nikiyaantonbettey.blogspot.com/search?q=biological+agent
Phosphatidylethanolamine (PE) is a class of phospholipids found in biological membranes.[1] They are synthesized by the addition of cytidine diphosphate-ethanolamine to diglycerides, releasing cytidine monophosphate. S-Adenosyl methionine can subsequently methylate the amine of phosphatidylethanolamines to yield phosphatidylcholines. It can mainly be found in the inner (cytoplasmic) leaflet of the lipid bilayer.[2]
Phosphatidylethanolamines are found in all living cells, composing 25% of all phospholipids. In human physiology, they are found particularly in nervous tissue such as the white matter of brain, nerves, neural tissue, and in spinal cord, where they make up 45% of all phospholipids.[3]
Phosphatidylethanolamines play a role in membrane fusion and in disassembly of the contractile ring during cytokinesis in cell division.[4] Additionally, it is thought that phosphatidylethanolamine regulates membrane curvature. Phosphatidylethanolamine is an important precursor, substrate, or donor in several biological pathways.[3]
As a polar head group, phosphatidylethanolamine creates a more viscous lipid membrane compared to phosphatidylcholine. For example, the melting temperature of di-oleoyl-phosphatidylethanolamine is -16 °C while the melting temperature of di-oleoyl-phosphatidylcholine is -20 °C. If the lipids had two palmitoyl chains, phosphatidylethanolamine would melt at 63 °C while phosphatidylcholine would melt already at 41 °C.[5]Lower melting temperatures correspond, in a simplistic view, to more fluid membranes.
https://en.wikipedia.org/wiki/Phosphatidylethanolamine
https://nikiyaantonbettey.blogspot.com/2021/08/08-29-2021-214-vacuolar-type-atpase-v.html
08-25-20210857 reverted to draft 1669/70-1,2 - Taliban Cheers! help my boyfriend was overvaccinated with vaccine small pox experiments 1900s draft collection missing files missing file illicit edit hacked by USA; usa injurying my files for centuries Plasmodium VAccinia Goldman 1960 NLAB pediatric infectious disease eczema vaccinatum HIV VIG IG globulin globulins hyperimmunity activation with deterior condeterior etc. Src and Abl family kinase phosphor phosphoryl phosphorous phosphorus P RecombinantAntigenProteinPoxviridaeSmallpox VaccineSmallpoxHuman Immunodeficiency VirusVaccinia Virus Vaccinia induced actin polymerization is dependent on Src and Abl family kinase mediated phosphorylation of the IEV protein A36 (Frischknecht et al., 1999; small pox overvaccination campaign/world scale operations/methroxetrate crops bacillus crops mollucum on kids/lipodystrophy/organ failure/reshelling/stolen intellectual property from VIV-NLAB-Grig/100 year ops ~1920-1960/undocumented trails/law breaking/HIV+ test pass??/etc. sharon petersen smith grayden walsh et al., etc.. - NLAB @ bioweap