In molecular biology, ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters.
ABC transporters belong to the ATP-Binding Cassette superfamily, which uses the hydrolysis of ATP to translocate a variety of compounds across biological membranes. ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These regions can be found on the same protein or on two different ones. Most ABC transporters function as a dimer and therefore are constituted of four domains, two ABC modules and two TMDs.
https://en.wikipedia.org/wiki/ATP-binding_domain_of_ABC_transporters
No comments:
Post a Comment