09-08-2021-1518 - Oxyphilic Adenocarcinoma Follicule oncocytic hurthle cell Thyroid endocrine endocrinology adeno SEER & PUBMED Process "...abundant granular eosinophilic cytoplasm (oncocytes)."

 Oxyphilic Adenocarcinoma

MedGen UID: 

61427

 •Concept ID: 

C0205642

 •

Neoplastic Process

Synonyms:	Adenocarcinoma, Oxyphilic; Adenocarcinomas, Oxyphilic; Oxyphilic Adenocarcinomas
SNOMED CT:	Follicular carcinoma, oxyphilic cell (57596004); Oxyphilic adenocarcinoma (443261008); Oxyphilic adenocarcinoma (57596004); Oncocytic carcinoma (57596004); Oncocytic adenocarcinoma (57596004); Hurthle cell carcinoma (57596004); Hurthle cell adenocarcinoma (57596004)

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Definition

An adenocarcinoma characterized by the presence of large malignant epithelial cells with abundant granular eosinophilic cytoplasm (oncocytes). Representative examples include thyroid gland oncocytic follicular carcinoma, oncocytic breast carcinoma, and salivary gland oncocytic carcinoma. [from NCI]

https://www.ncbi.nlm.nih.gov/medgen/61427

 https://seer.cancer.gov/icd-o-3/sitetype.icdo3.20210607.pdf#search=plasma%20cell

09-08-2021-0937 - Primary myelofibrosis (PMF) is a rare bone marrow blood cancer.[1] ' This is most often associated with a somatic mutation in the JAK2, CALR, or MPL gene markers. In PMF, the healthy marrow is replaced by scar tissue (fibrosis), '

 Primary myelofibrosis (PMF) is a rare bone marrow blood cancer.^[1] It is classified by the World Health Organization (WHO) as a type of myeloproliferative neoplasm, a group of cancers in which there is growth of abnormal cells in the bone marrow. This is most often associated with a somatic mutation in the JAK2, CALR, or MPL gene markers. In PMF, the healthy marrow is replaced by scar tissue (fibrosis), resulting in a lack of production of normal blood cells. Symptoms include anemia, increased infection and an enlarged spleen (splenomegaly).

In 2016, prefibrotic primary myelofibrosis was formally classified as a distinct condition that progresses to overt PMF in many patients, the primary diagnostic difference being the grade of fibrosis.^[2]

Primary myelofibrosis
Other names	PMF, Overt PMF, Myelofibrosis
Specialty	Oncology and Hematology

https://en.wikipedia.org/wiki/Primary_myelofibrosis

above. 

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