The Legionellales are an order of Proteobacteria. Like all Proteobacteria, they are Gram-negative.[2] They comprise two families, typified by Legionella and Coxiella, both of which include notable pathogens. For example, Q fever is caused by Coxiella burnetiiand Legionella pneumophila causes Legionnaires' disease[3][4] and Pontiac fever.[5][6][7]
Members of the order Legionellales can be molecularly distinguished from other Gammaproteobacteria by the presence of four conserved signature indels (CSIs) in the proteins tRNA-guanine(34) transglycosylase, lipoprotein-releasing system transmembrane protein lolE and tRNA (guanosine(37)-N1)-methyltransferase TrmD.[8]
| Legionellales | |
|---|---|
 | |
| Legionella sp. under ultraviolet illumination | |
Scientific classification | |
| Domain: | Bacteria |
| Phylum: | Proteobacteria |
| Class: | Gammaproteobacteria |
| Order: | Legionellales |
| Families and genera | |
Legionellaceae | |
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