Blog Archive

Monday, December 6, 2021

12-06-2021-1149 - viral vectors

 Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (in vivo) or in cell culture (in vitro). Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect. Delivery of genes or other genetic material by a vector is termed transduction and the infected cells are described as transduced. Molecular biologists first harnessed this machinery in the 1970s. Paul Berg used a modified SV40 virus containing DNA from the bacteriophage Î» to infect monkey kidney cells maintained in culture.[1]

In addition to their use in molecular biology research, viral vectors are used for gene therapy and the development of vaccines.

https://en.wikipedia.org/wiki/Viral_vector

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