Negri bodies are eosinophilic, sharply outlined, pathognomonic inclusion bodies (2–10 μm in diameter) found in the cytoplasm of certain nerve cells containing the virus of rabies, especially in pyramidal cells[1] within Ammon's horn of the hippocampus. They are also often found in the Purkinje cells[1] of the cerebellar cortex from postmortem brain samples of rabies victims. They consist of ribonuclear proteins produced by the virus.[2]
They are named for Adelchi Negri.[3]
Histopathology of Negri bodies in rabies encephalitis.
https://en.wikipedia.org/wiki/Negri_body
No comments:
Post a Comment