The Gammaretrovirus core encapsidation signal is an RNA element known to be essential for stable dimerisation and efficient genome packaging during virus assembly.[1]Dimerisation of the viral RNA genomes is proposed to act as an RNA conformational switch which exposes conserved UCUG elements and enables efficient genome encapsidation.[2] The structure of this element is composed of three stem-loops. Two of the stem-loops called SL-C and SL-D form a single co-axial extend helix.
| Gammaretrovirus core encapsidation signal | |
|---|---|
 Predicted secondary structure and sequence conservation of Gammaretro_CES | |
| Identifiers | |
| Symbol | Gammaretro_CES |
| Rfam | RF00374 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Eukaryota; Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
https://en.wikipedia.org/wiki/Gammaretrovirus_core_encapsidation_signal
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