A Jarisch–Herxheimer reaction is a reaction to endotoxin-like products released by the death of harmful microorganisms within the body during antibiotic treatment. Efficacious antimicrobial therapy results in lysis (destruction) of bacterial cell membranes, and in the consequent release into the bloodstream of bacterial toxins, resulting in a systemic inflammatory response.[citation needed]
Jarisch–Herxheimer reactions can be life-threatening as they can cause a significant drop in blood pressure and cause acute end-organ injury, eventually leading to multi-organ failure.[citation needed]
| Herxheimer reaction | |
|---|---|
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| Jarisch-Herxheimer reaction in a patient with syphilis and HIV infection | |
| Pronunciation | |
| Specialty | Infectious disease |
https://en.wikipedia.org/wiki/Jarisch%E2%80%93Herxheimer_reaction
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