08-29-2021-2137 - Phosphoesters form the backbone of DNA molecules. Nitrate esters, such as nitroglycerin, are known for their explosive properties.

Phosphoesters form the backbone of DNA molecules. Nitrate esters, such as nitroglycerin, are known for their explosive properties.

The word ester was coined in 1848 by a German chemist Leopold Gmelin,^[4] probably as a contraction of the German Essigäther, "acetic ether".

https://en.wikipedia.org/wiki/Ester

acetic acid, 

Ethyl acetate (systematically ethyl ethanoate, commonly abbreviated EtOAc, ETAC or EA) is the organic compound with the formula CH
3−COO−CH
2−CH
3, simplified to C
4H
8O
2. This colorless liquid has a characteristic sweet smell (similar to pear drops) and is used in glues, nail polish removers, and in the decaffeination process of tea and coffee. Ethyl acetate is the ester of ethanol and acetic acid; it is manufactured on a large scale for use as a solvent.^[5]

https://en.wikipedia.org/wiki/Ethyl_acetate

A phosphodiester bond occurs when exactly two of the hydroxyl groups in phosphoric acid react with hydroxyl groups on other molecules to form two ester bonds. The "bond" involves this linkage C-O-PO₂⁻-O-C.^[1] Discussion of phosphodiesters is dominated by their prevalence in DNA and RNA, but phosphodiesters occur in other biomolecules, e.g. acyl carrier proteins.

Phosphodiester bonds make up the backbones of DNA and RNA. The phosphate is attached to the 5' carbon. The 3' carbon of one sugar is bonded to the 5' phosphate of the adjacent sugar. ^[2]Specifically, the phosphodiester bond links the 3' carbon atom of one sugar molecule and the 5' carbon atom of another(hence the name, 3', 5' phosphodiester linkage ^[2]). These saccharide groups are derived from deoxyribose in DNA and ribose in RNA. Phosphodiesters are negatively charged at pH 7.^[3] Repulsion between these negative charges influences the conformation of the polynucleic acids. The negative charge attracts histones, metal cations such as magnesium, and polyamines.

In order for the phosphodiester bond to be formed and the nucleotides to be joined, the tri-phosphate or di-phosphate forms of the nucleotide building blocks are broken apart to give off energy required to drive the enzyme-catalyzedreaction.^[4]

Hydrolysis of phosphodiester bonds is catalyzed by phosphodiesterases, which are involved in repairing DNA sequences.^[5]

The phosphodiester linkage between two ribonucleotides can be broken by alkaline hydrolysis, whereas the linkage between two deoxyribonucleotides is more stable under these conditions. The relative ease of RNA hydrolysis is an effect of the presence of the 2' hydroxyl group.

https://en.wikipedia.org/wiki/Phosphodiester_bond

above. B R Right Trina ft. ludacris