Asfarviridae
- Bacteriophages
- Phycodnaviridae
- Virion
- Nucleocytoplasmic Large DNA Virus
- Genus
- Poxviridae
- Iridoviridae
- Mimivirus
- African Swine Fever Virus
- Domestic Pig
Asfarviridae
In Virus Taxonomy, 2012
Publisher Summary
This chapter focuses on the Asfarviridae family whose sole member genus is Asfivirus, popularly known as African swine fever virus(ASFV). The ASFV virions consist of a nucleoprotein core structure, which is 70–100 nm in diameter, surrounded by an internal lipid layer, an icosahedral capsid, and an external lipid-containing envelope. The virions are sensitive to ether, chloroform and deoxycholate, and are inactivated at 60 °C within 30 min, but survive for years at 20 °C or 4 °C. The genome consists of a single molecule of linear, covalently close-ended, dsDNA 170–190 kbp in size and the end sequences are present as two flip-flop forms that are inverted and complementary with respect to each other. The virions contain more than 50 proteins, including a number of enzymes and factors needed for early mRNA transcription and processing. Enzymes packaged into virions include the multisubunit RNA polymerase, polyA polymerase, guanylyl transferase, and protein kinase. The inhibitor of apoptosis (IAP) homolog protein is also packaged in the virions. The virus encodes components of a redox pathway, including the pB119L (or 9GL), pE248R and pA151R proteins, of which the pA151R and pB119L proteins are nonstructural. Other predicted proteins encoded by the virus include various enzymes involved in nucleotide metabolism such as ribonucleotide reductase, thymidine kinase, thymidylate kinase and deoxyuridine triphosphatase, and various enzymes involved in DNA replication and repair or transcription such as DNA polymerase, DNA polymerase X, DNA ligase, topoisomerase II, guanylyl transferase, three members of DNA helicase superfamily II, and AP endonuclease.
https://www.sciencedirect.com/topics/immunology-and-microbiology/asfarviridae
above. nicki minaj - hard white
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