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Thursday, August 26, 2021

08-26-2021-1412 - Menangle pararubulavirus

 Menangle pararubulavirus, also called Menangle virus, is a virus that infects pigshumans and bats.

Menangle is one of three recently discovered zoonotic viruses in Australia that are carried by bats. The others are Hendra virus and Australian bat lyssavirus (ABLV or bat rabies).

Like all paramyxoviruses, Menangle virus has an envelope, negative sense ssRNA, and pleomorphic (both spherical and elongated forms) proteins (HN and fusion) which protrude from the surface as spikes that help the virus get into cells. As an RNA virus, it must enter the cell to replicate.

Swine: Reduced conception rates; reduced litter size; large number of stillborn fetuses (some with severe skeletal/craniofacial defects); virus found in the lungs, brain and heart of stillborn piglets; No signs of illnesses in pigs of any age after birth.

Humans: Illness lasts for 10–14 days; fever; chills; rigors; drenching sweats; malaise; headache; red spotty rash.


Hydranencephaly: meaning the cerebral cortex has a large cavity where the cerebral hemispheres are missing and is instead filled with cerebrospinal fluid.

Limbs are often rigid and hyperflexed.

Uneven alignment of upper and lower teeth.

https://en.wikipedia.org/wiki/Menangle_pararubulavirus


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