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Sunday, August 29, 2021

08-29-2021-1253 - Oscivirus picornavirales picorna RNA osc A viroporins

 Oscivirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Birds serve as natural hosts. There is only one species in this genus: Oscivirus A.[1][2]

'Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and viroporins.'

https://en.wikipedia.org/wiki/Oscivirus


Viroporins are small and usually hydrophobic multifunctional viral proteins that modify cellular membranes, thereby facilitating virus release from infected cells.[2][3] Viroporins are capable of assembling into oligomeric ion channels or pores in the host cell's membrane, rendering it more permeable and thus facilitating the exit of virionsfrom the cell. Many viroporins also have additional effects on cellular metabolism and homeostasis mediated by protein-protein interactions with host cell proteins.[3] Viroporins are not necessarily essential for viral replication, but do enhance growth rates. They are found in a variety of viral genomes but are particularly common in RNA viruses. Many viruses that cause human disease express viroporins. These viruses include hepatitis C virusHIV-1influenza A viruspoliovirusrespiratory syncytial virus, and SARS-CoV.[3][4][5]

https://en.wikipedia.org/wiki/Viroporin

above. katy perty ET


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