08-29-2021-1401 - Q fever or query fever cox coxiella ella burn burnetti burnetii coxiella burnetii bacteria inhalation cattle sheep goat rodent arthropod crustecean bacteria viri cellular infectivity survival requirements time obligate intracellular pathogenic parasite immunohistochemical immunology histology pathology hematology radiology bruce brucellosis leptospirosis spirochete leprosy lupus HIV molluscum contagium poxiviridae neuro-granulation disseminative granulation non caseous plaque tuberculosis miliary caseous necrosis gangrene fulminant fulminancy bubules purulent bubulant rables; burna cox, cow chicken

C. burnetii, the Q fever-causing agent

Q fever or query fever is a disease caused by infection with Coxiella burnetii,^[1][3][4] a bacterium that affects humans and other animals. This organism is uncommon, but may be found in cattle, sheep, goats, and other domestic mammals, including cats and dogs. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus, or semenof infected animals. Rarely, the disease is tick-borne.^[5] The incubation period is 9–40 days. Humans are vulnerable to Q fever, and infection can result from even a few organisms.^[5] The bacterium is an obligate intracellular pathogenic parasite. 

In the natural environment, Legionella lives within amoebae such as Acanthamoeba spp., Naegleria spp.,  Vermamoeba vermiformis, or other protozoa such as Tetrahymena pyriformis.^[12]

Upon inhalation, the bacteria can infect alveolar macrophages, where the bacteria can replicate. This results in Legionnaires' disease and the less severe illness Pontiac fever. Legionella transmission is via inhalation of water droplets from a contaminated source that has allowed the organism to grow and spread (e.g., cooling towers). Transmission also occurs less commonly via aspiration of drinking water from an infected source. Person-to-person transmission has not been demonstrated;^[4] though, it could be possible in rare cases.^[13]

https://en.wikipedia.org/wiki/Q_fever

above. don mclean 

American Pie

Q feverOther namesQuery fever, coxiellosis^[1][2]Immunohistochemical detection of C. burnetii in resected cardiac valve of a 60-year-old man with Q fever endocarditis, Cayenne, French Guiana: Monoclonal antibodies against C. burnetii and hematoxylin were used for staining; original magnification is ×50.SpecialtyInfectious disease Typesacute, chronic^[1]Risk factorsContact with livestock^[2]Differential diagnosispneumonia, influenza, brucellosis, leptospirosis, meningitis, viral hepatitis, dengue fever, malaria, other rickettsial infections^[2]