Ranid herpesvirus 1 (RaHV-1), also known as the Lucké tumor herpesvirus (LTHV), is a double-stranded DNAvirus within the order Herpesvirales.[1][2][3][4] The virus was initially observed within renal tumors in 1934 by Baldwin Lucké, and more recently has become identifiable through the use of PCR in samples isolated from frog tumors. RaHV-1 causes renal tumors within the northern leopard frog, Rana pipiens. The virus has not yet been isolated in vitro within cell lines, meaning that while its existence and symptoms are fairly evident, its methods of transmission, cell infection, and reproduction are largely unknown.[5]
Since it has not been cultured in vitro, temporal studies regarding the kinetics of virus growth and biological and molecular events in the replication cycle have not been undergone extensively. Ranid herpesvirus 1, along with Ranid herpesvirus 2 and 3, are the only herpes viruses known to infect amphibians.[6]
https://en.wikipedia.org/wiki/Ranid_herpesvirus_1
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