Caseous necrosis or caseous degeneration[1] (/ˈkeɪsiəs/)[2] is a unique form of cell death in which the tissue maintains a cheese-like appearance.[3] It is also a distinctive form of coagulative necrosis.[4] The dead tissue appears as a soft and white proteinaceous dead cell mass.
Frequently, caseous necrosis is encountered in the foci of tuberculosis infections.[3] It can also be caused by syphilis and certain fungi.
A similar appearance can be associated with histoplasmosis, cryptococcosis, and coccidioidomycosis.[6]
Some data suggests that the epithelioid morphology and associated barrier function of host macrophages associated with granulomas may prevent effective immune clearance of mycobacteria.[9]
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https://en.wikipedia.org/wiki/Caseous_necrosis
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