Zero ionic layer is the main site of interaction in the core SNARE complex. Dipole-dipole interactions take place between 3 glutamine (Q) residues and 1 arginine (R) residue exposed in this layer. Despite that, the majority of the SNARE complex is hydrophobic because of the leucine zipper.[1] Extensively studied layers within the SNARE alpha-helical bundle are designated from "-7" to "+8". Zero ionic layer is at the center of the bundle, and thus designated as "0" layer.[2]
https://en.wikipedia.org/wiki/Zero_ionic_layer
https://en.wikipedia.org/w/index.php?title=Special:Search&limit=20&offset=20&profile=default&search=zero+dipole&ns0=1&searchToken=a0uxe9fl1p1mpqykx84iy22gq
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