Blog Archive

Tuesday, September 14, 2021

09-14-2021-0441 - Phikzvirus virus

 Phikzvirus (synonym: PhiKZ-like viruses, Phikzlikevirus before 2015) is a genus of virusesin the order Caudovirales, in the family Myoviridae. Bacteria serve as natural hosts. There are three species in this genus.[1][2][3]

Phages in this genus are considered large or "jumbo" phages. Three phages in this genus (φKZ, φPA3, and 201φ2-1) are known to assemble a "phage nucleus" structure similar in function to the eukaryotic cell nucleus that encloses DNA as well as replication and transcription machinery. These structures are built from a tubulin-like PhuZ protein and a gp105 shell protein. It provides immunity to host defenses like restriction enzymes and CRISPR-Cas systems.[4]

Phikzlikevirus EM.jpg
Electron micrograph of a Pseudomonas virus phiKZ virion

https://en.wikipedia.org/wiki/Phikzvirus

No comments:

Post a Comment