Phikzvirus (synonym: PhiKZ-like viruses, Phikzlikevirus before 2015) is a genus of virusesin the order Caudovirales, in the family Myoviridae. Bacteria serve as natural hosts. There are three species in this genus.[1][2][3]
Phages in this genus are considered large or "jumbo" phages. Three phages in this genus (φKZ, φPA3, and 201φ2-1) are known to assemble a "phage nucleus" structure similar in function to the eukaryotic cell nucleus that encloses DNA as well as replication and transcription machinery. These structures are built from a tubulin-like PhuZ protein and a gp105 shell protein. It provides immunity to host defenses like restriction enzymes and CRISPR-Cas systems.[4]
Electron micrograph of a Pseudomonas virus phiKZ virion |
https://en.wikipedia.org/wiki/Phikzvirus
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