CHAI disease is a rare genetic disorder of the immune system that illustrates the role of CTLA-4 in cell signaling. CHAI stands for “Autoimmune lymphoproliferative syndrome due to CTLA4 haplo-insufficiency.”[1][2] The disease is characterized by variable combination of enteropathy, hypogammaglobulinemia, recurrent respiratory infections, granulomatous lymphocytic interstitial lung disease, lymphocytic infiltration of non-lymphoid organs (intestine, lung, brain, bone marrow, kidney), autoimmune thrombocytopenia or neutropenia, autoimmune hemolytic anemia and lymphadenopathy.[1][3] It is closely linked to LATIAE disease.[1] Investigators in the laboratory of Dr. Michael Lenardo, National Institute of Allergy and Infectious Diseases at the National Institutes of Health first described this condition in 2018.[1][4]
https://en.wikipedia.org/wiki/CHAI_disease
RAS-associated autoimmune leukoproliferative disorder (RALD) is a rare genetic disorder of the immune system. RALD is characterized by lymphadenopathy, splenomegaly, autoimmunity, and elevation in granulocytes and monocytes. It shares many features with autoimmune lymphoproliferative syndrome and is caused by somatic mutations in NRAS or KRAS. This was first described by investigators João Oliveira and Michael Lenardo from the National Institutes of Health.[1]
https://en.wikipedia.org/wiki/RAS-associated_autoimmune_leukoproliferative_disorder
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.[2]
CREST syndrome is associated with detectable antibodies against centromeres (a component of the cell nucleus), and usually spares the kidneys (a feature more common in the related condition systemic scleroderma). If the lungs are involved, it is usually in the form of pulmonary arterial hypertension.
https://en.wikipedia.org/wiki/CREST_syndrome
Category:Autoimmune diseases
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Subcategories
This category has the following 11 subcategories, out of 11 total.
Pages in category "Autoimmune diseases"
The following 166 pages are in this category, out of 166 total. This list may not reflect recent changes (learn more).
A
- Acute disseminated encephalomyelitis
- Adrenergic receptor autoantibodies
- Alopecia areata
- Alopecia universalis
- Ankylosing spondylitis
- Anti-AQP4 disease
- Anti-IgLON5 disease
- Anti-VGKC-complex encephalitis
- Antiphospholipid syndrome
- Antisynthetase syndrome
- Aplastic anemia
- Apolipoprotein H
- Arthritis mutilans
- Atrophic gastritis
- Autoimmune autonomic ganglionopathy
- Autoimmune disease in women
- Autoimmune encephalitis
- Autoimmune enteropathy
- Autoimmune gastrointestinal dysmotility
- Autoimmune GFAP astrocytopathy
- Autoimmune hemolytic anemia
- Autoimmune hypophysitis
- Autoimmune inner ear disease
- Autoimmune oophoritis
- Autoimmune pancreatitis
- Autoimmune polyendocrine syndrome
- Autoimmune polyendocrine syndrome type 1
- Autoimmune polyendocrine syndrome type 2
- Autoimmune polyendocrine syndrome type 3
- Autoimmune retinopathy
- Autoimmune skin diseases in dogs
- Autoimmune/inflammatory syndrome induced by adjuvants
B
C
D
E
G
H
I
L
M
- Management of Crohn's disease
- Management of multiple sclerosis
- Marburg acute multiple sclerosis
- Marie Antoinette syndrome
- McDonald criteria
- McFall v. Shimp
- Microchimerism
- Mixed connective tissue disease
- Morphea
- Mucous membrane pemphigoid
- Multiple sclerosis research
- Multiple sclerosis signs and symptoms
- Myasthenia gravis
N
O
P
- Palindromic rheumatism
- PANDAS
- Paraneoplastic pemphigus
- Paul Patterson (neuroscientist)
- Pemphigoid
- Pemphigus
- Poser criteria
- Postorgasmic illness syndrome
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Proctitis
- Progressive inflammatory neuropathy
- Psoriasis
- Psoriatic arthritis
- Pulmonary alveolar proteinosis
R
S
- Samoyed hereditary glomerulopathy
- Sarcoidosis
- Satoyoshi syndrome
- Diffuse myelinoclastic sclerosis
- Schumacher criteria
- Scleroderma
- Scleromyositis
- Sebaceous adenitis
- Signs and symptoms of Graves' disease
- Simple clinical colitis activity index
- Sjögren syndrome
- Skin manifestations of sarcoidosis
- Susac's syndrome
- Sympathetic ophthalmia
- Systemic scleroderma
- Systemic vasculitides
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