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Monday, September 6, 2021

09-06-2021-0021 - Prenylation isoprenylation lipidation

 


Prenylation (also known as isoprenylation or lipidation) is the addition of hydrophobicmolecules to a protein or chemical compound. It is usually assumed that prenyl groups (3-methylbut-2-en-1-yl) facilitate attachment to cell membranes, similar to lipid anchors like the GPI anchor, though direct evidence of this has not been observed. Prenyl groups have been shown to be important for protein–protein binding through specialized prenyl-binding domains.
https://en.wikipedia.org/wiki/Prenylation

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