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Wednesday, August 11, 2021

08-10-2021-1754 - 2331 - SIV Lentivirus Simian

a lentivirus (species Simian immunodeficiency virus) that causes a disease in monkeys similar to AIDS and that is closely related to HIV-2

https://www.merriam-webster.com/dictionary/SIV

Structure and genome[edit]

The SIV virion is a spherical to pleomorphic glycoprotein envelope 110-120 nm enclosing a 110x50nm truncated cone or wedge-shaped (occasionally rod) capsid containing a dimeric pair of positive-sense single-stranded RNAgenome.

  • Related viruses also cause disease in other mammals: sheepgoatscatscattlehorses
  • SV40 is another virus that came from simians and into human populations in the mid twentieth century.

https://en.wikipedia.org/wiki/Simian_immunodeficiency_virus


Simian-T-lymphotropic viruses, also Simian T-cell leukemia viruses (STLVs), are retroviruses closely related to the human sexually and breastfeeding transmissible viruses HTLV. They have subtypes 1 through 4 as compared to HTLV 1 through 4, and each subtype has its own serovars.[1] Together they comprise PTLVs (primate T-lymphotropic viruses)[1] A study has shown that STLV-1 Tax and SBZ proteins have similar functions to their counterparts of HTLV-1. STLV-1 is oncogenic in Japanese macaques.[2]

In particular, the HTLV-I/STLV-I history might suggest a simian migration from Asia to Africa not much earlier than 19,500–60,000 years ago.[1]

https://en.wikipedia.org/wiki/Simian-T-lymphotropic_virus



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