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Thursday, September 2, 2021

09-02-2021-1056 - Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides (possible repost some posts missing)

 Mycosis fungoides, also known as Alibert-Bazin syndrome or granuloma fungoides,[1] is the most common form of cutaneous T-cell lymphoma. It generally affects the skin, but may progress internally over time. Symptoms include rash, tumors, skin lesions, and itchy skin.

While the cause remains unclear, most cases are not hereditary. Most cases are in people over 20 years of age, and it is more common in men than women. Treatment options include sunlight exposure, ultraviolet light, topical corticosteroidschemotherapy, and radiotherapy.

https://en.wikipedia.org/wiki/Mycosis_fungoides


Poikiloderma vasculare atrophicans (PVA), is a cutaneous condition (skin disease) characterized by hypo- or hyperpigmentation (diminished or heightened skin pigmentation, respectively), telangiectasia and skin atrophy.[3][4][5] Other names for the condition include prereticulotic poikiloderma and atrophic parapsoriasis.[6] The condition was first described by pioneer American pediatrician Abraham Jacobi in 1906.[7] PVA causes areas of affected skin to appear speckled red and inflamed, yellowish and/or brown, gray or grayish-black, with scaling and a thinness that may be described as "cigarette paper".[3] On the surface of the skin, these areas may range in size from small patches, to plaques (larger, raised areas), to neoplasms(spreading, tumor-like growths on the skin).[3][6]

Mycosis fungoides, a type of skin lymphoma, may be a cause of PVA. The condition may also be caused by, associated with or accompany any of the following conditions or disorders: other skin lymphomas, dermatomyositislupus erythematosusRothmund–Thomson syndromeKindler syndromedyskeratosis congenita, and chronic radiodermatitis.[4] Rare causes include arsenicingestion, and the condition can also be idiopathic.[1][3][5]

PVA may be considered a rare variant of cutaneous T-cell lymphoma, a non-Hodgkin's form of lymphoma affecting the skin.[7] It may also be included among a number of similar conditions that are considered as precursors to mycosis fungoides. PVA is believed to be a syndrome closely associated with large-plaque parapsoriasis and its cohort retiform parapsoriasis; including PVA, all three conditions fit within an updated view of the once ambiguous classification scheme known as parapsoriasis.[5]

https://en.wikipedia.org/wiki/Poikiloderma_vasculare_atrophicans

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