09-02-2021-1058 - Actinic granuloma dermal infiltrate of macrophages Tumid lupus erythematosus Pyoderma gangrenosum

 Actinic granuloma is a cutaneous condition characterized histologically by a dermal infiltrate of macrophages.^[1]:706

Actinic granuloma is an asymptomatic granulomatous reaction that affects sun-exposed skin, most commonly on the face, neck, and scalp. It is characterized by annular or polycyclic lesions that slowly expand centrifugally and have an erythematous elevated edge and a hypopigmented, atrophic center. Advise to reduce exposure to the sun and to use sunscreen. Treatment with topical halometasone cream, pimecrolimus cream.

https://en.wikipedia.org/wiki/Actinic_granuloma

Tumid lupus erythematosus is a rare, but distinctive entity in which patients present with edematous erythematous plaques, usually on the trunk.^[2]

Lupus erythematosus tumidus (LET) was reported by Henri Gougerot and Burnier R. in 1930. It is a photosensitive skin disorder, a different subtype of cutaneous lupus erythematosus (CLE) from discoid lupus erythematosus (DLE) or subacute CLE (SCLE).^[3] LET is usually found on sun-exposed areas of the body. Skin lesions are edematous, urticarialike annular papules and plaques. Topical corticosteroids are not effective as treatment for LET, but many will respond to chloroquine. LET resolves with normal skin, no residual scarring, no hyperpigmentation or hypopigmentation. Cigarette smokers who have LET may not respond very well to chloroquine.^[4][5]

It has been suggested that it is equivalent to Jessner lymphocytic infiltrate of the skin.^[6]

https://en.wikipedia.org/wiki/Tumid_lupus_erythematosus

Pyoderma gangrenosum is a rare, inflammatory skin disease where painful pustules or nodulesbecome ulcers that progressively grow.^[3] Pyoderma gangrenosum is not infectious.^[3]

Treatments may include corticosteroids, ciclosporin, infliximab, or canakinumab.^[2]

The disease was identified in 1930. It affects approximately 1 person in 100,000 in the population. Though it can affect people of any age, it mostly affects people in their 40s and 50s.^[1]

https://en.wikipedia.org/wiki/Pyoderma_gangrenosum