High-pressure nervous syndrome (HPNS – also known as high-pressure neurological syndrome) is a neurological and physiological diving disorder which can result when a diver descends below about 500 feet (150 m) using a breathing gas containing helium. The effects experienced, and the severity of those effects, depend on the rate of descent, the depth and the percentage of helium.[1]
"Helium tremors" were first widely described in 1965 by Royal Navy physiologist Peter B. Bennett, who also founded the Divers Alert Network.[1][2] Russian scientist G. L. Zal'tsman also reported on helium tremors in his experiments from 1961. However, these reports were not available in the West until 1967.[3]
The term high-pressure nervous syndrome was first used by Brauer in 1968 to describe the combined symptoms of tremor, electroencephalography (EEG) changes, and somnolence that appeared during a 1,189-foot (362 m) chamber dive in Marseille.[4]
HPNS has two components, one resulting from the speed of compression and the other from the absolute pressure.
Those suggest that helium might cause substantial lipid membrane distortion. The high hydrostatic pressure itself has a less damaging influence on the membrane,reducing molecular volumes, but leaving the molecular boundary intact.[6]
https://en.wikipedia.org/wiki/High-pressure_nervous_syndrome
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